Clinico-microbiological profile of Burkholderia cepacia keratitis: a case series

Abstract Background Burkholderia cepacia , an opportunistic pathogen mainly affecting patients with cystic fibrosis or immunocompromised, has rarely been documented as a cause of corneal infection. The clinical and microbiological profiles B. keratitis are reported herein. Methods We retrospectively reviewed the medical record 17 culture-proven keratitis, treated between 2000 2019 at Chang Gung Memorial Hospital, Taiwan. Our data included predisposing factors, presentations, treatments, visual outcomes well drug susceptibility causative agent. Results most common factor for was preexisting ocular disease (seven, 41.2%), particularly herpetic (five). Polymicrobial infection detected in seven (41.2%) eyes. All isolates were susceptible to ceftazidime. Main treatments levofloxacin Surgical treatment required five (29.4%) patients. Only four (23.5%) exhibited final acuity better than 20/200. Conclusions primarily affects disease, responds ceftazidime fluoroquinolones. However, generally poor.